Hey gentlemen, at in2GREAT we focus on functional, root cause health and healing.  While there is a lot of noise out in the media, social, and amongst friends about how to “biohack” your system.  While that is appealing and there is some value there, in our practice we see many men struggling with health issues that often go unaddressed or simply pushed under the rug. You’re taught to be tough, to push through, to ignore the whispers of your bodies. Ignoring those whispers can lead to serious problems down the line. Today, I want to talk about men’s hormone health—a topic often shrouded in silence but one that deserves our full attention

This isn’t about simply boosting testosterone levels. It’s about understanding the intricate web of your hormonal system and addressing the root causes of imbalances, a core foundational principle of functional medicine. Think of your body as a finely tuned orchestra. When one instrument is out of tune, the whole performance suffers. The same thing occurs in the body when one hormone is out of balance, it can trigger a cascade of adverse effects throughout your entire system.

The Silent Epidemic: Why Men’s Hormone Health Matters

Many men experience hormonal imbalances without even realizing it. Symptoms might be dismissed as “just getting older,” “stress,” or even just “being a man.” But symptoms like fatigue, low libido, weight gain (especially around the belly), mood swings, decreased muscle mass, and even cognitive decline can all be signs of underlying hormonal imbalances. These aren’t just inconveniences; they can significantly impact your quality of life, relationships, and overall well-being.

Beyond Low T: A Holistic Approach to Hormone Health

The traditional medical approach often focuses on treating symptoms rather than identifying and addressing the root causes. For example, low testosterone is usually treated with testosterone replacement therapy (TRT). While TRT can be helpful in some cases, it doesn’t address the underlying issues contributing to low testosterone. Often times in our practice we observe an excessive conversion into estrogens, which if not understood and managed correctly can itself lead into a plethora of chronic inflammatory complications. In functional medicine, we take a different approach. We look at the bodys systems and how they are working together, from the central nervous system to the gastrointestinal system to the endocrine system and more.

Key Factors Contributing to Hormonal Imbalances:

  • Insulin Resistance is a major culprit. High blood sugar and insulin resistance disrupt the production of crucial hormones like progesterone and DHEA (a precursor to both testosterone and estrogen). This can lead to aromatization—the conversion of testosterone to estrogen, resulting in estrogen dominance. High insulin levels also fuel inflammation and oxidative stress, further damaging your system.
  • Inflammation: Chronic inflammation silently wreaks havoc on your body. It interferes with hormone production, disrupts your HPA (hypothalamic-pituitary-adrenal) axis (stress response system), and overworks the liver.
  • Impaired Liver Detoxification: Your liver is your body’s primary detox organ. When it’s overworked or damaged by toxins (including xenoestrogens, which mimic estrogen), it can’t effectively metabolize hormones and remove excess toxins, disrupting hormonal balance.
  • Estrogen Dominance and Xenoestrogens: These environmental estrogens, found in plastics, pesticides, personal care products, and even some foods, overload your system, contributing to estrogen dominance and hormonal chaos.
  • Chronic Stress & Cortisol: Chronic stress keeps your body constantly alert, leading to high cortisol levels. This suppresses testosterone production, increases aromatization, promotes insulin resistance, and breaks down tissues – a vicious cycle.
  • Lack of Exercise or the wrong exercise for your body: A sedentary lifestyle increases body fat, particularly visceral fat (around your organs), further boosting aromatase activity, converting testosterone into estrogen. It also contributes to insulin resistance and reduces growth hormone production. Another key variable we have to consider is based on your genetic profile and how your unique system is hardwired – what is even the best exercise approach for you?  The wrong approach can amplify all of the above mentioned complications.

What Can You Do? A Functional Medicine Approach

The good news is that you can take control of your hormone health. A functional medicine approach focuses on:

  • Identifying and Addressing Root Causes: This involves comprehensive testing to evaluate your thyroid function, adrenal function, sleep quality, stress levels, nutrient deficiencies, gut health, toxin burden, underlying chronic infections and more and if needed your genetics
  • Balancing Hormones, Not Just Boosting Testosterone: We aim to restore the delicate balance of your hormonal system, not just artificially increase testosterone. Often, this means addressing insulin resistance, inflammation, liver detoxification, and stress management and properly looking further upstream on the hormone cascade.  Are you in a catabolic state, anabolic state, etc.
  • Lifestyle Changes: This is crucial. It includes:
    • How you eat: An anti-inflammatory approach to eating that prioritizes clean protein and healthy fats, keeps carbohydrates to a minimum, and eliminates grains, sugar, and processed foods.
    • Exercise: Regular exercise, especially strength training, is essential for naturally boosting testosterone, reducing body fat, and improving insulin sensitivity. Plus, it’s a great mood balancer.
    • Stress Management: Incorporate stress-reducing techniques like meditation, yoga, or spending time in nature. And prioritize sleep!
    • Nutrient Optimization: Focus on nutrients crucial for hormone production, such as zinc, magnesium, vitamin D, B vitamins and omega 3 fatty acids.
    • Limiting Exposure to Xeno-estrogens: Be mindful of the products you use and the food you eat, choosing options that are free from harmful chemicals.
    • Supplements, peptides and  Bio-Identical Hormone Replacement Therapy (BHRT): Using supplements, peptides, and bio-identical hormone replacement therapy to enhance nutrition, detoxification, methylation, digestion, or hormone balance can be beneficial. However, it is crucial that these interventions are recommended and monitored by a skilled practitioner. In today’s modern world, there is an overwhelming amount of information about how to “bio-hack” your health, including advice from platforms like ChatGPT suggesting supplement recommendations. This can be a dangerous route to take. The plethora of information available on social media and other outlets can lead to confusion and misinformation. Ultimately, using supplements, hormones, and the allure of peptides without proper guidance can become merely a band-aid solution and may pose significant risks if not handled responsibly. A genuine understanding of physiological and biological mechanisms is necessary to know what supplements, peptides, and BHRT to use and how to apply them correctly in order to address disturbances or imbalances in your body. Simply reading the ingredients on a supplement label may not provide the safety and efficacy you assume. Products may contain low-quality ingredients, potentially making them more toxic than if you had not taken them at all. The current peptide landscape resembles the wild west; many individuals are using peptides for weight loss, fat burning, or muscle gain without comprehending the implications for their unique physiology. It is vital to assess whether the underlying issues are being addressed prior to pursuing these approaches and to ensure that the peptides are sourced from labs that manufacture them safely and reliably.
  • Know Your Levels: Getting a comprehensive hormone panel is key to understanding your current state. It is also great to assess labs at all stages in life, so you can understand the trends. This allows for personalized interventions and progress monitoring. Here are some key labs we often utilize in a functional approach to men’s hormone health:
    • Testosterone (Total & Free): Indicates the overall and biologically active testosterone levels.
    • SHBG (Sex Hormone-Binding Globulin): This protein binds to testosterone, affecting the amount available for your body to use.
    • Estrogens: Measuring different types of estrogen, such as Estrone and Estradiol, helps assess potential estrogen dominance.
    • Prostate health markers (PSA Total & PSA Free) are important for monitoring prostate health, especially in conjunction with other hormone levels.
    • Brain hormones (FSH/LH): These hormones regulate testosterone production.
    • Adrenal hormones (DHEA-S, Cortisol): Assessing adrenal function is vital, as it plays a role in hormone balance and stress response.
    • Blood sugar (Glucose, A1c, Insulin, Lipids and subfractions): Essential for evaluating insulin resistance.
    • Inflammation markers (hs-CRP, Homocysteine): High levels indicate chronic inflammation, impacting hormone production.

It’s Time for a Change

Gentlemen, your health is not a luxury; it’s a necessity. Ignoring hormonal imbalances is not a sign of strength; it’s a recipe for long-term health problems. Don’t wait until things become critical. Take charge of your health now, and let’s work together to optimize your hormonal balance and help you live a vibrant, fulfilling life. Contact us today to schedule a consultation today and begin your journey toward better health.

Dr Corey Priest, DC - Functional medicine practitioner

About the author

Dr. Corey Priest has been practicing functional medicine since 2001. in2GREAT was founded in 2014 by Dr Priest after 13 years of experience with his other practices. Over his career, Dr. Priest has worked with and helped well over 10,000 patients under a functional medicine model.

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